Siglec 10 antibody
WebAK007 is a humanized Siglec-10 antagonist antibody designed to block Siglec-10 interaction with all known ligands (CD24, CD52, and VAP-1). Preclinical studies have demonstrated that monotherapy treatment with a … WebBuy rabbit polyclonal antibody to SIGLEC10 (A54002). Applications: ELISA, IP and WB. Reactivity: Human and Rat. ️ Low Prices ️ 100% Guarantee. Useful Links. 01223 298 ...
Siglec 10 antibody
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WebNov 29, 2024 · The anti-Siglec-10 (clone 5G6) was used as a blocking antibody to inhibit the CD24-Siglec-10 axis, and robustly improved the phagocytosis of tumour cells by … WebJul 4, 2014 · Siglec-10 (human homolog of mouse Siglec-G) was detected on all B cells and also subsets of human leukocytes including eosinophils, monocytes and a minor …
WebSIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3- or 2,6-linked sialic acid. The sialic acid recognition … WebApr 10, 2024 · The Siglec-Fc protein, a fusion protein combining Siglec with the Fc part of a human antibody, is a promising sialic acid-Siglec axis-targeted agent for cancer treatment and is widely used for Siglec ligands discovery. The recombinant Siglec-Fc fusion protein has been expressed in different cell systems. However, its characteristics have not ...
WebThere are no reviews for Siglec-10 Antibody (NBP1-82759). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount. Review with no image -- … WebAntibody information for antibodies HPA027093 and CAB025807 used in analysis of ENSG00000142512 / SIGLEC10 (MGC126774, PRO940, SIGLEC-10, SLG2) We use cookies …
WebRabbit SIGLEC10 Rabbit pAb (A20413), validaed in WB and tested in Human,, Rat. 100% Guaranteed. ABclonal provides trial size antibody samples for target detection. …
WebSIGLEC10 antibody LS-C187565 is an unconjugated mouse monoclonal antibody to human SIGLEC10. Validated for Flow. Products. Research Areas. COVID-19. Resources. ... (NK) cells. Structurally, Siglec-10 is most similar to the CD33-related group of Siglecs, and preferentially binds to glycoconjugates containing alpha-2,3- or alpha-2,6-linked sialic ... develop smart contract ethereumWebSiglec-10 is a lectin that specifically binds α-2,3- or α-2,6-linked sialic acid. It is a member of the Ig-superfamily and is expressed in monocytes, eosinophils, B cells, and a subset of NK … develop software using pythonWebIn cancer it is important to consider the mode of action of CD24-Fc. The binding to Siglec-10 on immune effector cells as an agonist could render cells more immunosuppressive. In … develop social phrases eyfsWebSiglec-15, which selectively drives immunosuppression in the tumor microenvironment, has emerged as a viable therapeutic target. In a phase I trial of NC318, a Siglec-15 antibody, … churches in whiteford mdWebSiglec-10 is a sialic acid-binding Ig-like lectin that has been shown to negatively regulate innate and adaptive immune system function (1). Siglec-10 is a type 1 transmembrane … develop software requirements specificationdevelop self-awareness as a teacherWebWe offer Siglec-10 Antibodies for use in common research applications: Blockade of Receptor-ligand Interaction, ELISA, Flow Cytometry, Immunohistochemistry, … develop sophisticated care plans