WebThe class III region of the HLA complex is located between the class I and class II regions. Whereas HLA class I and class II genes encode sets of structurally related, highly polymorphic transplantation antigens, the class III region consists of at least four types of genes, only two of which have obvious functions in the immune system. WebMay 23, 2024 · The class II MHC genes encode glycoproteins expressed primarily on antigen-presenting cells (macrophages, dendritic cells, and B cells), where they present processed antigenic peptides to TH cells. The class II proteins are encoded by the HLA-D region and the HLA-D regions have three families, DP-, DQ-, and DR-encoded molecules.
MHC Class I, Class II, Antigen Processing, And Presentation
WebNational Center for Biotechnology Information WebJan 9, 2009 · The human leukocyte antigen (HLA) super-locus is a genomic region in the chromosomal position 6p21 that encodes the six classical transplantation HLA genes and … milton picture framing
Clinical and immunological aspects of HLA class I deficiency
WebPubMed WebNov 7, 2024 · The association of autoimmune diseases with HLA has been known for many decades. To date, however, the underlying mechanisms have not been fully understood. … WebHLA is the human version of the major histocompatibility complex (MHC), a gene family that occurs in many species. Genes in this complex are categorized into three basic groups: … milton place apartments wv