WebHas a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 … WebFeb 17, 2024 · Bub1 is a conserved kinase critical for the spindle assembly checkpoint. Bub1 also facilitates chromosome alignment and contributes to the regulation of mitotic …
Bub1 autophosphorylation feeds back to regulate kinetochore ... - Nature
WebApr 4, 2024 · Jika dilihat secara teknis, kedua prosedur ini tidak jauh berbeda. CT scan dan MSCT sama-sama menggabungkan sinar-X dan teknologi komputer untuk menghasilkan gambar tubuh secara melintang. Tapi, teknologi yang ada pada MSCT ternyata jauh lebih canggih dibanding CT scan. Baca juga: 7 Jaringan Tubuh yang Bisa Dideteksi … WebJan 19, 2024 · In conclusion, BUB1 mutations cause a neurodevelopmental disorder, with clinical and cellular phenotypes that partially resemble previously described syndromes, … inga smith-forbes
Inhibitors of the Bub1 spindle assembly checkpoint kinase: …
WebAug 1, 2024 · BUB1 expression was up-regulated in Saos2, U2OS and 143B cells, with the highest levels being expressed in U2OS and Saos2 cells (Figure 1C). FIGURE 1. Open in figure viewer PowerPoint. Expression of BUB1 protein in osteosarcoma (OS) tissues and cell lines. A, Representative images of different staining intensities of BUB1 protein in … WebMar 15, 2010 · BubR1 (Bub1-related kinase or MAD3/Bub1b) is an essential component of the spindle assembly checkpoint (SAC) and plays an important role in kinetochore … WebMIB1 A monoclonal antibody which recognises a formalin-fixation-resistant epitope on the cell proliferation-associated Ki-67 antigen. MIB1 is a reliable marker of cell proliferation, … inga share price